diff --git a/dnscrypt-proxy/example-dnscrypt-proxy.toml b/dnscrypt-proxy/example-dnscrypt-proxy.toml
index 5520272e..7afcc1c6 100644
--- a/dnscrypt-proxy/example-dnscrypt-proxy.toml
+++ b/dnscrypt-proxy/example-dnscrypt-proxy.toml
@@ -183,7 +183,9 @@ log_files_max_backups = 1
 ## Immediately respond to IPv6-related queries with an empty response
 ## This makes things faster when there is no IPv6 connectivity, but can
 ## also cause reliability issues with some stub resolvers. In
-## particular, enabling this on macOS is not recommended.
+## particular, enabling this on macOS is not recommended. Also do not
+## enable if you added a validating resolver such as dnsmasq in front of
+## the proxy.
 
 block_ipv6 = false