diff --git a/mtu_discoverer.go b/mtu_discoverer.go
index d2d1ac77..fd1f6679 100644
--- a/mtu_discoverer.go
+++ b/mtu_discoverer.go
@@ -98,6 +98,11 @@ type mtuFinder struct {
 	lost             [maxLostMTUProbes]protocol.ByteCount
 	lastProbeWasLost bool
 
+	// The generation is used to ignore ACKs / losses for probe packets sent before a reset.
+	// Resets happen when the connection is migrated to a new path.
+	// We're therefore not concerned about overflows of this counter.
+	generation uint8
+
 	tracer *logging.ConnectionTracer
 }
 
@@ -110,10 +115,15 @@ func newMTUDiscoverer(
 ) *mtuFinder {
 	f := &mtuFinder{
 		inFlight: protocol.InvalidByteCount,
-		min:      start,
 		rttStats: rttStats,
 		tracer:   tracer,
 	}
+	f.init(start, max)
+	return f
+}
+
+func (f *mtuFinder) init(start, max protocol.ByteCount) {
+	f.min = start
 	for i := range f.lost {
 		if i == 0 {
 			f.lost[i] = max
@@ -121,7 +131,6 @@ func newMTUDiscoverer(
 		}
 		f.lost[i] = protocol.InvalidByteCount
 	}
-	return f
 }
 
 func (f *mtuFinder) done() bool {
@@ -162,7 +171,7 @@ func (f *mtuFinder) GetPing(now time.Time) (ackhandler.Frame, protocol.ByteCount
 	f.inFlight = size
 	return ackhandler.Frame{
 		Frame:   &wire.PingFrame{},
-		Handler: &mtuFinderAckHandler{f},
+		Handler: &mtuFinderAckHandler{mtuFinder: f, generation: f.generation},
 	}, size
 }
 
@@ -170,13 +179,26 @@ func (f *mtuFinder) CurrentSize() protocol.ByteCount {
 	return f.min
 }
 
+func (f *mtuFinder) Reset(now time.Time, start, max protocol.ByteCount) {
+	f.generation++
+	f.lastProbeTime = now
+	f.lastProbeWasLost = false
+	f.inFlight = protocol.InvalidByteCount
+	f.init(start, max)
+}
+
 type mtuFinderAckHandler struct {
 	*mtuFinder
+	generation uint8
 }
 
 var _ ackhandler.FrameHandler = &mtuFinderAckHandler{}
 
 func (h *mtuFinderAckHandler) OnAcked(wire.Frame) {
+	if h.generation != h.mtuFinder.generation {
+		// ACK for probe sent before reset
+		return
+	}
 	size := h.inFlight
 	if size == protocol.InvalidByteCount {
 		panic("OnAcked callback called although there's no MTU probe packet in flight")
@@ -207,6 +229,10 @@ func (h *mtuFinderAckHandler) OnAcked(wire.Frame) {
 }
 
 func (h *mtuFinderAckHandler) OnLost(wire.Frame) {
+	if h.generation != h.mtuFinder.generation {
+		// probe sent before reset received
+		return
+	}
 	size := h.inFlight
 	if size == protocol.InvalidByteCount {
 		panic("OnLost callback called although there's no MTU probe packet in flight")
diff --git a/mtu_discoverer_test.go b/mtu_discoverer_test.go
index 415d0638..733d0517 100644
--- a/mtu_discoverer_test.go
+++ b/mtu_discoverer_test.go
@@ -197,3 +197,53 @@ func testMTUDiscovererWithRandomLoss(t *testing.T) {
 	t.Logf("probes sent (%d): %v", len(probes), probes)
 	require.LessOrEqual(t, diff, maxMTUDiff)
 }
+
+func TestMTUDiscovererReset(t *testing.T) {
+	t.Run("probe on old path acknowledged", func(t *testing.T) {
+		testMTUDiscovererReset(t, true)
+	})
+	t.Run("probe on old path lost", func(t *testing.T) {
+		testMTUDiscovererReset(t, false)
+	})
+}
+
+func testMTUDiscovererReset(t *testing.T, ackLastProbe bool) {
+	const startMTU protocol.ByteCount = 1000
+	const maxMTU = 1400
+	const rtt = 100 * time.Millisecond
+
+	rttStats := &utils.RTTStats{}
+	rttStats.SetInitialRTT(rtt)
+
+	now := time.Now()
+	d := newMTUDiscoverer(rttStats, startMTU, maxMTU, nil)
+	d.Start(now)
+
+	ping, _ := d.GetPing(now.Add(5 * rtt))
+	ping.Handler.OnAcked(ping.Frame)
+	require.Greater(t, d.CurrentSize(), startMTU)
+	now = now.Add(5 * rtt)
+
+	// send another probe packet, but neither acknowledge nor lose it before resetting
+	ping, _ = d.GetPing(now.Add(5 * rtt))
+	now = now.Add(2 * rtt) // advance the timer by an arbitrary amount
+
+	const newStartMTU protocol.ByteCount = 900
+	const newMaxMTU = 1500
+	d.Reset(now, newStartMTU, newMaxMTU)
+	require.Equal(t, d.CurrentSize(), newStartMTU)
+
+	// Now acknowledge / lose the probe packet.
+	// This should be ignored, since it's on the old path.
+	if ackLastProbe {
+		ping.Handler.OnAcked(ping.Frame)
+	} else {
+		ping.Handler.OnLost(ping.Frame)
+	}
+
+	// the MTU should not have changed
+	require.Equal(t, d.CurrentSize(), newStartMTU)
+	// the next probe should be sent after 5 RTTs
+	require.False(t, d.ShouldSendProbe(now.Add(5*rtt).Add(-time.Microsecond)))
+	require.True(t, d.ShouldSendProbe(now.Add(5*rtt)))
+}